Endocrine Abstracts

Introduction: Autoimmune polyglandular syndrome (APS) is an autoimmune disorder that affects many endocrine glands. Until now four categories of APS are identified: APS-I includes at least two out of: mucocutaneous candidiasis, hypoparathyroidism and adrenocortical failure. APS-II, the most frequent, comprises of Addison’s disease, autoimmune thyroid disease and/or type 1 diabetes. APS-III is defined by the presence of autoimmune thyroid disease and other autoimmune disor...

Introduction: Turner syndrome (ST) affects 1/2500–1/4000 of female births, its association with congenital malformations is traditional, however the coexistence of hypopituitarism is exceptional. In this context, we report 6 patients; including 3 belonging to the same family and in whom the association of anterior pituitary insufficiency (IAH) to a ST was confirmed.Results: The average age of our patients was 17.2 years (11–31). The ST was sele...

IntroductionTriple-A syndrome, also known as Allgrove syndrome, is a rare autosomal recessive disorder. It is a multisystemic disease with an estimated prevalence of 1 per 1 000 000 individuals The 3 features of this syndrome are achalasia, adrenal insufficiency, and alacrima. Recently, dental impairment has been the subject of several case reports and reviews. However, this abnormality remains under-diagnosed.Purpose<p class="...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...

IntroductionMitochondrial diseases are a clinically heterogeneous group of disorders that arise as a result of dysfunction of the mitochondrial respiratory chain.it is genetically heterogeneous diseases characterized by multisystem involvement. Thus, its clinical description is incomplete. The aim of this case report is to highlight the association between mitochondrial diabetes and severe hypertriglyceridemia. In this study, we describe the case of a 22...

IntroductionType 1 diabetes (T1D), also known as juvenile diabetes, commonly occurs in young individuals. However, autoimmune diabetes may be diagnosed in the elderly, with different clinical and biological aspects. The aim of our study is to identify the prevalence of and risk factors for microvascular complications related to T1D diagnosed during adulthood.Patients and methodsA retrospective study, from 201...

IntroductionThe prevalence of childhood obesity continues to increase nowadays but also its long-term complications, particularly metabolic and cardiovascular, and this is due in large part to all the current modern conditions and means that promote sedentary lifestyle and lack of ’physical activityMaterial and methodsWe developed a 16-week aerobic exercise program (four 60-minute sessions per week at 70...

BackgroundIt’s well known that smoking and diabetes are direct causes for serious health problems such as cancer, and atherosclerosis. It is suggested that smoking indirectly leads to atherosclerosis by influencing nutrient intakes as smokers tend to eat more fat and carbohydrates and less mono unsaturated fats and fiber than non-smokers. But no studies assessed the impact of tobacco on nutrition in diabetic patients.Aim<p...

IntroductionDiabetes mellitus is a serious metabolic disease, described by the World Health Organization as a global epidemic. An alarming increase in its prevalence among adults is observed in Tunisia as everywhere else in the world. Because type 2 diabetes preponderates among adults, few epidemiological studies focused on type 1 diabetes (T1D) that occurs during the adulthood. The aim of this study is to determine the prevalence of DT1 among Tunisian a...

IntroductionMasked arterial hypertension (HTAM) is a relatively recently described entity which gives patients with it the same cardiovascular risk as permanent hypertension. In this context, we report a prospective study including 53 patients in order to determine the prevalence and predictive factors of HTAM in diabetics.MethodsDescriptive prospective study of 53 patients treated in the endocrinology Diabet...